Investigating neurotransmitters by high-sensitivity proton MRS
Not Applicable
- Conditions
- brain diseases
- Registration Number
- JPRN-UMIN000022286
- Lead Sponsor
- ational Institutes for Quantum and Radiological Science and Technology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 24
Inclusion Criteria
Not provided
Exclusion Criteria
1. Persons who have brain diseases 2. Substance dependence 3. Persons who have serious complications or persons who had serious complications before which are not appropriate for this study based on the judgement of the researcher/doctor. 4. Persons who have a pacemaker or any metal in his body 5. Persons who have a tatoo 6. Persons who have serious claustrophobia 7. Pregnancy 8. Other persons who are determined by the researcher/doctor.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method A) Optimization of imaging parameters B) evaluation of the sensitivity for measuring neurotransmitters by SPECIAL and MEGA-PRESS
- Secondary Outcome Measures
Name Time Method 1. Gender difference of brain metabolites 2. Regional distribution of brain metabolites 3. Association between brain and plasma metabolites