Electrocardiograph Changes and Holter Abnormalities in Children With Predialytic Chronic Kidney Disease

Recruiting

• Conditions: Predialytic Chronic Kidney Disease

• Registration Number: NCT05726071
• Lead Sponsor: Sohag University

Brief Summary

CKD is a strong risk factor for cardiovascular disease and mortality , As in adults, cardiovascular disease occurs in some children with CKD before they reach ESRD as well as after

Detailed Description

This work aims to study the electrophysiological changes in cardiovascular system in children with predialytic CKD. ECG is important in detection of cardiac rhythm abnormalities, cardiac conduction defects and detection of myocardial ischemia

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2022-11-01
• Status Verified: 2023-01
• Study First Submitted: 2023-01-31
• Study First Submitted QC: 2023-02-09
• Last Update Submitted: 2023-02-09
• Study First Posted: 2023-02-13
• Last Update Posted: 2023-02-13
• Primary Completion: 2023-10-01
• Study Completion: 2023-10-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Age 1 to 15 year children with predialytic chronic kidney disease GFR.>15 ml\min per 1.73m2 , stages 1, 2, 3, 4 according to (KDOQI stages).

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Exclusion Criteria

• Age >15 year On regular dialysis GFR<15 ml\min per 1.73m2, Stage 5 according to (KDOQI stages). Children with known cardiovascular disease or known arrhythmia Patients on the potential medication affecting ECG result as B-blocker, antipsychotics , antidepressant

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
QRS duration	One year	Increase or decrease in ECG
Heart rate variability	One year	Sinus tachycardia or bradycardia
changes in QT interval	One year	Prolonged QT interval in ECG

Trial Locations

Locations (1)

Sohag faculty of medicine; 🇪🇬 Sohag, Egypt