Tremor in Dystonia and Essential tremor.
Recruiting
- Conditions
- English: Dystonic tremor, Dystonia, Essential tremor, tacsDutch: Tremor bij Dystonie, Dystonie, Essentiële tremor, tacs, beven
- Registration Number
- NL-OMON29165
- Lead Sponsor
- Donders Institute for Brain, Cognition and Behaviour. Centre for Cognitive Neuroimaging.Kapittelweg 29 6525 EN Nijmegen
- Brief Summary
.A.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 32
Inclusion Criteria
Essential tremor:
-Clinical diagnosis of essential tremor
Exclusion Criteria
-Neurological co-morbidity
-Moderate to severe head tremor (to avoid artifacts caused by extensive head motion during scanning)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) phase specific tremor power suppression during M1 tacs, in ET vs DT<br /><br>2) phase specific tremor power suppression during Cerebellar tacs, in ET vs DT<br /><br>3) Phase specific tremor related cerebral activity during cerebellar tacs, in ET vs DT
- Secondary Outcome Measures
Name Time Method -Tremor related cerebral activity and connectivity, compared between dystonic and essential tremor.<br /><br>-GABA concentrations in GPi, cerebellum and primary motor cortex, compared between dystonic and essential tremor.<br /><br><br>