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Clinical Trials/NCT06138093
NCT06138093
Completed
Not Applicable

Consequence of Open Versus Closed Tracheostomy Immediately After Decannulation

Aarhus University Hospital1 site in 1 country20 target enrollmentFebruary 28, 2020
ConditionsTracheostomy

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Tracheostomy
Sponsor
Aarhus University Hospital
Enrollment
20
Locations
1
Primary Endpoint
Forced expiratory volume in one second (FEV1)
Status
Completed
Last Updated
last year

Overview

Brief Summary

Tracheostomy is performed for prolonged mechanical ventilation. Ineffective bandaging following decannulation leaves the tracheostomy wound unsealed, reducing pulmonary function, coughing ability, and voice quality, ultimately leading to decannulation failure. Recently, a new concept enabling intratracheal sealing of the tracheotomy was introduced, potentially solving the issues of air leakage and tracheal wound infection. This study aims to investigate the feasibility of intratracheal tracheostomy sealing in relation to an immediate normalization of physiological airway flow and an improved voice quality.

Detailed Description

See protocol document.

Registry
clinicaltrials.gov
Start Date
February 28, 2020
End Date
June 1, 2023
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Aarhus University Hospital
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Tracheostomy for minimum 7 days
  • Age \> 18 years
  • Capped uncuffed tube size 7 or 8 for at least 24 hours

Exclusion Criteria

  • Cognitive dysfunction (patients who are not able to cooperate with investigation)

Outcomes

Primary Outcomes

Forced expiratory volume in one second (FEV1)

Time Frame: Day 2: At time of decannulation, i.e. directly after inclusion and randomization to sealing or not as first intervention

Lung function / air flow evaluated by spirometry

Voice quality

Time Frame: Day 2: At time of decannulation, i.e. directly after inclusion and randomization to sealing or not as first intervention

Evaluated by Equal-Appearing Interval Scale ranging from 1 to 5, where 5 represents a normal voice quality and 1 represents a severely impaired voice

Peak expiratory flow (PEF)

Time Frame: Day 2: At time of decannulation, i.e. directly after inclusion and randomization to sealing or not as first intervention

Lung function / air flow evaluated by spirometry

Forced vital capacity (FVC)

Time Frame: Day 2: At time of decannulation, i.e. directly after inclusion and randomization to sealing or not as first intervention

Lung function / air flow evaluated by spirometry

Study Sites (1)

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