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Clinical Trials/NCT05418530
NCT05418530
Unknown
Not Applicable

Effect of Closed Tracheal Aspiration Associated With Expiratory Pause in Pediatrics: A Randomized, Crossover Clinical Study

Hospital Israelita Albert Einstein1 site in 1 country40 target enrollmentApril 22, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Respiratory Insufficiency in Children
Sponsor
Hospital Israelita Albert Einstein
Enrollment
40
Locations
1
Primary Endpoint
secretion mass
Last Updated
3 years ago

Overview

Brief Summary

Introduction: Patients on mechanical ventilation suffer alterations in the viscoelastic characteristics of the mucus due to changes in the humidity and temperature of the inhaled air and in the respiratory volumes and flows. The literature has pointed out the use of mechanical ventilators as a tool for mobilizing secretions and closed-system aspiration associated with expiratory pause has been shown to be effective in mobilizing secretions. Objectives: To assess whether there is a difference in the mass of aspirated secretion with the application of the expiratory pause during aspiration. Methods: A crossover, randomized study. Applied to children aged 0 to 5 years and 11 months who are intubated for 24 hours with orotracheal tubes or tracheostomy. There will be an exclusion of patients who present with undrained pneumothorax, cranial hypertension or any other clinical situation that has a clinical contraindication to aspiration and patients whose parents do not agree to participate in the study. The technique will be during aspiration in the tube with where to apply or not the expiratory pause on the mechanical ventilator. This secretion will be weighed so that there is fidelity in the results.

Detailed Description

A prospective, crossover, randomized clinical study will be carried out in the Pediatric ICU of Hospital Israelite Albert Einstein.

Registry
clinicaltrials.gov
Start Date
April 22, 2022
End Date
December 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients aged 0 to 5 years and 11 months who have been on invasive mechanical ventilation for more than 24 hours through an orotracheal cannula or tracheostomy will be included in the study.

Exclusion Criteria

  • Patients who present with undrained pneumothorax, cranial hypertension or any other clinical situation that has a clinical contraindication to aspiration and patients whose parents do not agree to participate in the study will be excluded from the study.

Outcomes

Primary Outcomes

secretion mass

Time Frame: 6 hours

The secretion will be weighed on a scale graduated in milligrams.

Secondary Outcomes

  • tidal volume(6 hours)

Study Sites (1)

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