Estimation of a clot end-product called D-Dimer in different stages of pregnancy with establishment of a normal value for Tasmanian women.
Not Applicable
Completed
- Conditions
- The association of D-Dimer levels with normal pregnancy and also high risk pregnancy, DIC, venous thromboembolic (VTE) and pregnancy loss.Reproductive Health and Childbirth - Normal pregnancy
- Registration Number
- ACTRN12609000225213
- Lead Sponsor
- Assoc Professor Alhossain Khalafallah
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 700
Inclusion Criteria
Pregnant women 18 years old and above.
Exclusion Criteria
Age less than 18 years.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The statistical establishment of normal D-dimer levels in each trimester of pregnancy supported by haematological evaluation and well-being questionnaires.[Blood sample once per trimester of pregnancy.]
- Secondary Outcome Measures
Name Time Method The seconday outcome will be to determine and evaluate the optimum diagnostic thresholds for D-Dimer levels as predictors of adverse pregnancy outcomes. This will be done by monitoring D-Dimer levels whilst assessing patients for indicators of adverse pregnancy outcomes. This will be acheived through the use of haematological assessment, the use of well-being questionnaires and hospital records of patients' admission for treatment of pathology during pregnancy.[Blood sampled once per trimester in pregnancy, with monthly blood samples from women whose D-Dimer level was higher than the estimated average normal range inpregnancy.]