The physiologic study of high-flow oxygen delivery via tracheostomy in patients requiring mechanical ventilatio

Not Applicable

Completed

• Conditions: Tracheostomized patients who require ventilator support; High- flow oxygen therapy; Tracheostomy; Respiratory Failure

• Registration Number: TCTR20180612001
• Lead Sponsor: Faculty of Medicine Siriraj Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-06-12
• Study Completion: 2019-10-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

1. Age 18-90 years
2. Tracheostomized patients
3. Ready to be weaned (pressure support 4. Glasgow Coma Scale > 8

Exclusion Criteria

1. Unstable hemodynamics (systolic BP > 180 and/or < 90 mmHg, diastolic BP > 100 and/or < 60 mmHg, heart rate > 140 and/or < 60/min, or clinical signs of shock)
2. Respiratory distress (RR > 35/min or SpO2 < 92%)
3. Acid-base disturbance (pH < 7.3 or > 7.55)
4. Contraindications for esopheageal balloon insertion (upper GI bleeding, esophageal varices, esophageal or gastric surgery within 3 months, platelet < 50,000 cu.mm.or coagulopathy)
5. Pregnant woman

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Patient inspiratory effort 30 minutes Esophageal pressure-time product

Secondary Outcome Measures

Name	Time	Method
Respiratory rate 30 minutes breath/minute,Hemodynamics (heart rate and mean arterial blood pressure) 30 mintues beat/min and mmHg,Oxygen saturation 30 minutes Pulse oximetry (%),Transcutaneous carbon dioxide pressure 30 minutes mmHg