MedPath

Seasonal Allergic Rhinitis and Driving Ability

Phase 4
Terminated
Conditions
Seasonal Allergic Rhinitis
Interventions
Other: 1 week of treatment discontinuation
Registration Number
NCT00223587
Lead Sponsor
Utrecht Institute for Pharmaceutical Sciences
Brief Summary

On-the-road driving performance of untreated seasonal allergic rhinitis patients during the allergic season (exposed) is compared to driving performance outside the allergic season (in winter, not-exposed).

Detailed Description

This study was set-up to examine whether untreated seasonal allergic rhinitis has an effect on driving ability. In addition to the driving tests, patients perform a memory test in the laboratory.

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
22
Inclusion Criteria
  • outpatients with seasonal allergic rhinitis
  • a valid driver's licence
  • written informed consent
  • a T5SS score >8 during the allergic season and <3 in winter
Exclusion Criteria
  • use of medication or medical conditions that are known to affect driving ability
  • associated ENT disease or asthma

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
A1 week of treatment discontinuation1 week of treatment discontinuation
Primary Outcome Measures
NameTimeMethod
Driving test: Standard Deviation of Lateral Position (SDLP, cm); i.e. the weaving of the car [after 1 week of treatment discontinuation]allergic season and winter
Secondary Outcome Measures
NameTimeMethod
Other driving test parameters: standard deviation of speed, mean speed, meal lateral position [after 1 week of treatment discontinuation]allergic season and winter
Memory test: immediate and delayed recall, delayed recognition [after 1 week of treatment discontinuation]allergic season and winter

Trial Locations

Locations (1)

Utrecht Institute for Pharmaceutical Sciences

🇳🇱

Utrecht, Netherlands

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