KCT0006735
Recruiting
未知
Identification of candidate gene for pathologic myopia in Korean using exome wide association study
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Yonsei University Health System, Severance Hospital
- Enrollment
- 250
- Status
- Recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Those who are 3 years of age or older at the time of selection and meet the conditions of ? or ?
- •? Refractive error\> \-6\.0D or axial length\> or \= 26\.5mm and myopic CNV was diagnosed.
- •? Diagnosis Criteria for Myopic CNV: When one of subretinal hemorrhage, hyperreflective lesion, intraretinal fluid, subretinal fluid, or RPE detachement is found on OCT (Ocular Optical Tomography).
- •? Refractive error\> \-9\.0D or axial length\> 28mm, and there is a family history of pathologic myopia.
- •Pathologic myopia criteria (one of the following)
- •? Refractive error\> \-9\.0D or axial length\> 28mm
- •? Have a history of Myopic maculopathy or posterior staphyloma
Exclusion Criteria
- •? If the selection criteria are satisfied, but have a history of other retinal diseases such as diabetic retinopathy, uveitis, retinopathy of prematurity, and senile macular degeneration.
- •? If the selection criteria are satisfied, but there is a history of being diagnosed with other systemic diseases that may cause high myopia (Stickler syndrome, Marshall syndrome, Wagner syndrome, Ehlers Danlos syndrome, etc.)
Outcomes
Primary Outcomes
Not specified
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