Optimising heat therapy for treating high blood pressure
Not Applicable
Recruiting
- Conditions
- HypertensionCardiovascular - Hypertension
- Registration Number
- ACTRN12622000720718
- Lead Sponsor
- niversity of Otago
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Participants will be screened as per criteria listed below:
-Aged > 35 y or older
-Prescribed and regularly taking at least 1 anti-hypertensive medication
-Patient gives written consent
-Patient is able to travel to the study centre to complete all sessions.
Exclusion Criteria
-Aged < 35 y
-Contraindication to maximal exercise testing (see Appendix)
-Unstable angina
-Recent myocardial infarction (< 3 months ago)
-History of orthostatic intolerance/hypotension
-Current pregnancy
-New anti-hypertensive pharmaceutical initiated recently
-Any other medical condition deemed a significant risk to study participation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood pressure (assessed via ausculatory method and ambulatory method)[Pre-exposure, during exposure, immediately post-exposure and across 24-h post exposure.]
- Secondary Outcome Measures
Name Time Method Blood pressure regulatory markers (antidiuretic hormone, atrial natiruetic peptide, haemaglobin, haematocrit; collected via venous blood sample)[Pre-exposure, immediate post-exposure and 24-h post exposure];Physical activity (assessed via accelerometery)[Across the 24-h post exposure.];Heart rate (assessed via chest strap)[Pre-exposure, during exposure and immediately post-exposure.];Body composition (assessed via bioimpedence analysis)[Pre-exposure and 24-h post-exposure. ];Vascular function (assessed via ultrasound)[Pre-exposure, during exposure and immediately post-exposure.]