The change in metabolic rate and the factors involved in systemic metabolic adaptation after acute exercise in healthy male subjects in the 3rd-4th decades

Overview

No summary available.

Registry

who.int

Start Date

TBD

End Date

November 28, 2017

Last Updated

4 years ago

Study Type

Interventional Study

Sex

All

Sponsor

•1\) Healthy men aged 20 to 40 at the time of screening
•2\) Those with a body weight of 50 kg or more and a body mass index of 18\.5 or more and less than 30
•3\) Those who do not have congenital or chronic diseases that require treatment and do not have pathological symptoms or abnormal findings as a result of medical examination and physical examination.
•4\) A person who is determined to be suitable as a clinical trial subject as a result of laboratory tests and physical examinations such as serum tests, hematology tests, blood chemistry tests, and urinalysis tests set and conducted according to the characteristics of the drug during the screening test.
•5\) A person who voluntarily decides to participate and agrees in writing to observe the precautions after hearing detailed explanation of this clinical trial and fully understanding it.

•1\) Diabetic patients
•2\) Intense exercise within the last 1 week or moderate or higher exercise within 24 hours
•3\) People with NYHA class I or higher breathing difficulties
•4\) Patients with underlying cardiovascular or respiratory disease
•5\) History of chest pain or fainting
•6\) Hemoglobin \<12 g/dL
•7\) Patients with active liver disease or those whose AST, ALT exceeds twice the upper limit of the normal range
•8\) Decreased renal function: eGFR \<60 ml per minute/1\.73 square meter
•9\) Systolic blood pressure \>150 mmHg or \<90 mmHg, or diastolic blood pressure \>100 mmHg or \<60 mmHg, or those who are taking antihypertensive drugs after diagnosis of hypertension
•10\) Those whose heart rate is less than 50 beats per minute at rest or who are contraindicated with beta blockers (propranolol)