Perceived Barriers to Patient Adherence After Pediatric Solid Organ Transplantation
- Conditions
- Organ Transplantation
- Registration Number
- NCT01370746
- Brief Summary
In this study, doctors will observe how and when pediatric patients who have received a solid organ transplant take their prescribed medication, and determining if there are reasons that keep these patients from taking all of their medicine.
- Detailed Description
Adhering to treatment regimens after solid organ transplantation is critical for the prevention of complications, including acute and chronic organ rejection. It is important to recognize the perceived barriers to following treatment regimens and identify ways to address these barriers early in the course of treatment.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 502
- Subject and/or guardian must be able to understand and provide informed consent/assent in English or Spanish
- Male or female primary solid organ transplant patients 0-21 years of age
- Recipients at least 1 month post-transplant hospital discharge
- Inability or unwillingness of a participant or parent/guardian to give informed consent or comply with study protocol
- Condition or characteristic which in the opinion of the investigator makes the participant unlikely to complete the questionnaires
- Re-transplant recipient
- Multi-organ transplant recipient
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Perceived barriers to adherence in adolescents and parent/legal guardian of pediatric patients 1 month post transplant Barriers assessed using Brief Medication Questionnaire (BMQ); Adolescent Medication Barrier Scales questionnaire (AMBS); and Parent Medication Barriers Scale questionnaire (PMBS)
Change in perceived barriers to adherence from baseline to follow-up 12 months post transplant Barriers assessed using Brief Medication Questionnaire (BMQ); Adolescent Medication Barrier Scales questionnaire (AMBS); and Parent Medication Barriers Scale questionnaire (PMBS)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (15)
Baylor College of Medicine/Texas Children's Hospital
🇺🇸Houston, Texas, United States
Children's Hospital of Boston
🇺🇸Boston, Massachusetts, United States
Ronald Reagan UCLA Medical Center (Mattel Childrens')
🇺🇸Los Angeles, California, United States
Nationwide Children's Hospital
🇺🇸Columbus, Ohio, United States
Emory Children's Center
🇺🇸Atlanta, Georgia, United States
The Cleveland Clinic
🇺🇸Cleveland, Ohio, United States
Lucile Packard Children's Hospital at Stanford
🇺🇸Stanford, California, United States
University of Florida Health Sciences Center
🇺🇸Gainesville, Florida, United States
Children's Hospital of Philadelphia
🇺🇸Philadelphia, Pennsylvania, United States
Children's Hospital and Regional Medical Center
🇺🇸Seattle, Washington, United States
Washington University School of Medicine
🇺🇸Saint Louis, Missouri, United States
Children's Hospital of New York
🇺🇸New York, New York, United States
University of Alabama
🇺🇸Birmingham, Alabama, United States
University of California San Francisco Children's Hospital
🇺🇸San Francisco, California, United States
University of Pittsburgh School of Medicine
🇺🇸Pittsburgh, Pennsylvania, United States