Analysis of Ventilation Weaning Strategies and Correlation to Outcomes in Tracheostomized Patients in the Intensive Care Unit of the Lausanne University Hospital

简要总结

主要结局

次要结局

• Height(At ICU admission)
• Comorbidities(At ICU admission)
• Age(At ICU admission)
• Predicted body weight (PBW)(At ICU admission)
• Sedation opioid use from intubation to tracheotomy(Once every day at 8am and at time of minimal and maximal value, between day of intubation to day of tracheotomy, up to 60 days)
• Tracheotomy time(At time of tracheotomy, once, up to 60 days after intubation day)
• Body mass index(At ICU admission)
• Opioid use from intubation to tracheotomy(Once every day at 8am and at time of minimal and maximal value, between day of intubation to day of tracheotomy, up to 60 days)
• Weight(At ICU admission)
• SOFA score (admission)(At ICU admission)
• Clinical Frailty Score(At ICU admission)
• Ventilation settings and modalities from day of tracheotomy(2 hours before tracheotomy)
• Physical therapy sessions from tracheotomy to mechanical ventilation weaning(Once every day at 8am and at time of minimal and maximal value, from day of tracheotomy to day of mechanical ventilation weaning, up to 31 days)
• Hospital stay duration(Once, between day of hospital admission to day of hospital discharge, up to 2 years)
• Charlson comorbidity index(At ICU admission)
• SOFA score (mechanical ventilation weaning day)(Once (3rd consecutive day with less than 12-h of mechanical ventilation), up to 31 days after tracheotomy day)
• Ventilation modalities and settings from mechanical ventilation weaning day to decannulation or ICU discharge or death(Once every day at 8am and at time of minimal and maximal value, from day of mechanical ventilation weaning to decannulation or ICU discharge or death, up to 31 days)
• Outcome and specific treatments in ICU(Once, between day of hospital admission to day of hospital discharge, up to 2 years)
• Ventilation modalities and settings from intubation to tracheotomy(Once every day at 8am, between day after intubation to day before tracheotomy, up to 60 days)
• SOFA score (tracheotomy day)(Once, on the day of tracheotomy (worst value of the day of tracheotomy), up to 60 days after intubation day)
• Mechanical ventilation weaning day(Once (day 3 in a row of less than 12 hours of mechanical ventilation), up to 31 days after tracheotomy day)
• Physical therapy sessions from mechanical ventilation weaning day to decannulation or ICU discharge or death(Once every day at 8am and at time of minimal and maximal value, from day of mechanical ventilation weaning to decannulation or ICU discharge or death, up to 31 days)
• Neuromuscular blocking agent use from intubation to tracheotomy(Once every day at 8am and at time of minimal and maximal value, between day of intubation to day of tracheotomy, up to 60 days)
• Tracheotomy type (percutaneous, surgical)(At time of tracheotomy, once, up to 60 days after intubation day)
• Ventilation modalities and settings from tracheotomy to mechanical ventilation weaning(Once per day, from day of tracheotomy to mechanical ventilation weaning, up to 60 days)
• Tracheotomy weaning strategies from tracheotomy to mechanical ventilation weaning(Once every day at 8am and at time of minimal and maximal value, from day of tracheotomy to day of mechanical ventilation weaning, up to 31 days)
• Correlation of ventilation settings and modalities and tracheotomy weaning strategies(Once, between day of hospital admission to day of hospital discharge, up to 2 years)