DRKS00021695尚未招募不适用
Observational and diagnostical study on transient allostastic responses of thyroid function after cardiopulmonary resuscitation. - Thyro-CPR
Abteilung für Endokrinologie und Diabetologie Medizinische Klinik I Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH UK RUB0 个研究点目标入组 200 人开始时间: 2020年5月8日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 200
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 one（—）
- 性别
- All
入选标准
- •Protocol A: Admission after cardiopulmonary resuscitation, minimum age of 18 years.
- •Protocol B: Admission after cardiopulmonary resuscitation, minimum age of 18 years, results of TSH and peripheral thyroid hormone concentrations already available or possibility to reorder these investigation in a post-hoc manner if consent has been obtained (i. e. time interval after venipuncture within the storage period of the central laboratory), inclusion after own consent of thepatient after reawakening, via custodian or independent consultant.
排除标准
- •Protocol A:Missing data on thyroid homeostasis in the first blood specimen (obtained before 3 hours after admission), traumatic brain injury, persistent hints for thyroid dysfunction (not explained by NTIS/ESS/TACITUS) in consecutive investigations over several days after resuscitation, functionally relevant thyroid or pituitary disorder, as documented in ICD codes.
- •Protocol B: Exposure to radiocontrast agents less than 3 months ago, therapy with amiodarone (currently or during the previous 3 years), traumatic brain injury, pregnancy, known thyroid disease, consent not obtained within the routine storage period of the central laboratory, post-hoc-exclusion if evidence for true dysfunction the pituitary or the thyroid became available during the study period.
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