Establishing elevated lipoprotein(a) as a target in calcific aortic valve disease - CALCIFY

Academisch Medisch Centrum0 个研究点目标入组 72 人开始时间: 待定最近更新: 2024年4月15日

适应症

试验速览

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•In order to be eligible to participate in this study, a subject must meet all of the following criteria:
•- Adult patients, aged 45-80 years old
•- Mild to moderate aortic valve stenosis: on echocardiography, aortic valve maximum velocity is >2.0 m/sec

•A potential subject who meets any of the following criteria will be excluded from participation in this study:
•- Severe aortic valve stenosis
•- History of radiotherapy of the thorax
•- History of rheumatic fever
•- Renal insufficiency, defined as eGFR < 30 ml/min
•- Hyperparathyroidism
•- Paget*s disease of the bone
•- Any other treatment or clininically relevant condition that could interfere with the conduct or interpretation of the study in the opinion of the investigator
•- Standard contra-indications to PET/CT

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