Evaluation of Retinal Vascular Density in High Myopia Without Pathological Myopic Maculopathy Using OCTA .

Not Applicable

Recruiting

• Conditions: High Myopia
• Interventions: Other: optical coherence tomography angiography

• Registration Number: NCT06596408
• Lead Sponsor: Sohag University

Brief Summary

Study aiming to evaluate Macular Vascular Density in High Myopes without pathological myopic maculopathy in outpatient clinic in Sohag teaching hospital using OCTA .

Detailed Description

Study Design : This is a cross sectional observational study , of about 50 patients attending ophthalmology outpatient clinic at Sohag Teaching Hospital .

Inclusion criteria :

All myopic patients with axial high myopia (-6 spherical refractive error or more) attending the ophthalmology outpatient clinic .

Exclusion criteria :

The exclusion criteria will include :

* History of other any ocular diseases , systemic diseases that may affect the ocular circulation .

* Previous intraocular surgery or ocular injury .

* Any patient with pathological myopic maculopathy (epiretinal membrane, foveoschisis, macular holes, lamellar holes, Lacquers cracks, choroidal neovascularization and retinal atrophy ) .

Study Timeline

• Study First Submitted: 2024-08-30
• Status Verified: 2024-09
• Study Start: 2024-09-11
• Study First Submitted QC: 2024-09-11
• Last Update Submitted: 2024-09-11
• Study First Posted: 2024-09-19
• Last Update Posted: 2024-09-19
• Primary Completion: 2025-09
• Study Completion: 2025-10

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
High Myopes of spherical error -6 and more .	optical coherence tomography angiography	About 50 participants with high myopia will undergo evaluation of their macular vascular density using OCTA and also central macular thickness using OCT.

Primary Outcome Measures

Name	Time	Method
Outcome of evaluation of vascular density in high myopes	6 month	Correlation between macular vascular density in high myopes and their : Uncorrected visual acuity in diopters . Best corrected visual acuity in diopters . Spherical equivalent refraction that measured through this equivalent (spherical error + 1/2 cylindrical error ) .; Central macular thickness in micrometers .; To see how does ischemia affects vision in high myopes .

Trial Locations

Locations (1)

Sohag University; 🇪🇬 Sohag, Egypt