macular and Macular and peripapillary vessel density in non-arteritic anterior ischemic optic neuropathy
- Conditions
- Macula vascular densityoptical coherence tomography angiographyA total of consecutive patients diagnosed as unilateral or bilateral non-acute non-arteritic anterior ischemic optic neuropathy by neuro-ophthalmologist in Songklanagarind HospitalNon-arteritic anterior ischemic optic neuropathy
- Registration Number
- TCTR20190722003
- Lead Sponsor
- Prince of Songkla University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 20
(1)History of a sudden onset of painless vision loss
(2)VF defect confined to only one hemifield consistent with NAION
(3)Optic disc edema at onset that was confirmed by at least one neuro-ophthalmology expert
(4)no evidence of other ocular diseases such as glaucoma, arteritic anterior ischemic optic neuropathy, optic neuritis, or coexisting retinal pathologies that may cause the visual symptoms or affected retinal and choroidal vascular.
(5) resolution of the initial optic disc and retinal edema at least 3 month after acute optic disc swelling.
(1) Patients age younger than 20 years or older than 80 years
(2) previous intraocular surgery
(3) Patients with poor image quality including images with poor clarity, motion artifact, and scans with signal strength index of <40 were excluded.
(4)Patients with unreliable visual field e.g. fixation losses and false-positive and false-negative results more than 33% were excluded.
(5)Refractive error greater than +3.0 diopters (D) or less than - 6.0 D
(6)Refractive error greater than 5.0 D of spherical equivalent or 3.0 D of astigmatism.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method percentage of the macular superficial vessel density (SVD) After patient complete the measurements optical coherence tomography angiography (OCTA)
- Secondary Outcome Measures
Name Time Method percentage of the peripalillary capillary density(PCD) After patient complete the measurements optical coherence tomography angiography (OCTA)