periapical healing evaluation after root end surgery with different retro filling materials with or without platelet rich fibrin

Completed

• Conditions: endodontic lesions not responding to conventional root canal treatment

• Registration Number: CTRI/2020/02/023443
• Lead Sponsor: Dr Vipul Gupta

Brief Summary

The purpose of this study is the Evaluation of periapical healing of the lesion after an endodontic microsurgery with different retrograde filling materials, with or without Platelet Rich Fibrin (PRF) autologous material.

Total of 60 subjects with lesion not responding to conventional root canal treatment will be selected and endodontic microsurgery will be done. Retrograde root preparation will be done and subjects will be randomly divided into 4 groups of 15 members each based on the root end filling materials. Different retrograde filling materials(MTA, Biodentine) will be used with or without platelet rich fibrin.

wound healing will be evaluated radiographically by measuring the volume of the lesion using CBCT after 12 months post operation.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-02-25
• Study Completion: 2021-11-21
• Last Update Posted: 2021-12-23

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1.Endodontic lesions not responding to conventional root canal treatments 2.Non-contributory medical history (ASA class I and class II) 3.Lesion involving 1-3 roots 4.Overfilled canals 5.Separated instrument in the apical half 6.Ledge formation or transportation in the canal 7.Anatomically complex root canal configurations.

Exclusion Criteria

1.Medically compromised patient (ASA class III to class VI) 2.Fractured tooth 3.Periodontally compromised patients 4.Through and through defects 5.Close Proximity to critical anatomical structures.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The purpose of this study is the Evaluation of periapical healing of the lesion after an endodontic microsurgery with different retrograde filling materials, with or without Platelet Rich Fibrin (PRF) autologous material.	1 week | 3 months | 6 months | 12 months

Secondary Outcome Measures

Name	Time	Method
The purpose of this study is the Evaluation of periapical healing of the lesion after an endodontic microsurgery with different retrograde filling materials, with or without Platelet Rich Fibrin	1 week

Trial Locations

Locations (1)

Faculty of Dental Sciences SGT University Gurugram Haryana; 🇮🇳 Gurgaon, HARYANA, India

Faculty of Dental Sciences SGT University Gurugram Haryana

🇮🇳Gurgaon, HARYANA, India

Dr Vipul Gupta

Principal investigator

8867901392

vipulgupta12d3268@gmail.com