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临床试验/NCT06349005
NCT06349005已完成不适用

Hemodynamic Response to Various Laryngoscopes During Tracheal Intubation in CABG Patients

Konya Meram State Hospital2 个研究点 分布在 2 个国家目标入组 112 人开始时间: 2025年1月12日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
112
试验地点
2
主要终点
Hemodynamic response

研究概览

简要总结

In this prospective, randomized, controlled trial, the purpose is to compare Macintosh laryngoscope, EzVision® video laryngoscope, McGrath® video laryngoscope and Storz® video laryngoscope in terms of hemodynamic response associated with intubation in adult patients undergoing Coronary Artery Bypass Surgery (CABG).

详细描述

During endotracheal intubation, laryngoscopy can significantly affect hemodynamic responses, including tachycardia and elevated blood pressure, which may be particularly detrimental to individuals with cardiovascular conditions. Various studies have explored the hemodynamic reactions associated with laryngeal stimulation through different intubation devices. Researchers hypothesize that endotracheal intubation using video laryngoscopy will elicit a reduced hemodynamic response compared to traditional (Macintosh) laryngoscopy. In this prospective and randomized clinical study, the purpose is to compare the Macintosh laryngoscope, EzVision® video laryngoscope, McGrath® video laryngoscope and Storz® video laryngoscope concerning haemodynamic response associated with intubation in adult patients undergoing Coronary Artery Bypass Surgery (CABG).

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age range between 18 and 75 years.
  • Scheduled for elective coronary artery bypass surgery.
  • Classified under American Society of Anesthesiologists (ASA) physical status II-III.
  • Patients with no history of difficult intubation or associated risk factors.

排除标准

  • Emergency case
  • Predicted difficult airways
  • Body mass index > 35 kilograms per meter squared
  • Baseline hemodynamic instability

结局指标

主要结局

Hemodynamic response

时间窗: Change from baseline heart rate at 10 minutes

Change from baseline heart rate

次要结局

  • Intubation time(180 seconds)
  • Visualization of the glottis(180 seconds)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Betul Kozanhan

Prof. Dr

Konya Meram State Hospital

研究点 (2)

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