NL-OMON56946
Not yet recruiting
Not Applicable
Multiomics in systemic inflammation driven brain aging in humans - UNCOVERS
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Radboud Universitair Medisch Centrum
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Planned for elective thoraco\-abdominal aortic aneurysm repair that also have an
- •ELD as part of their routine clinical care at Radboudumc
Exclusion Criteria
- •\- Disease states associated with a state of neuroinflammation: brain or spinal
- •surgery within the last 6 months, meningitis or brain infection within the last
- •6 months, presence of a CSF catheter or shunt, presence of known brain tumor,
- •brain injury (e.g., stroke, or subarachnoid hemorrhage) within the last 12
- •months, moderate\-severe brain trauma in previous medical history, chronic
- •active alcoholism or substance use.
- •\- Pre\-existing dementia or neurodegenerative disease
- •\- Cognitive impairment interfering with the ability to understand informational
- •study material.
- •\- Chronic (\>2 weeks) use of immunosuppressive agents (see table 3\.3\.A, below)
Outcomes
Primary Outcomes
Not specified
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