Spironolactone AmiLoride Thiazide study of aldosterone sensitive hypertensio

Completed

• Conditions: ow-renin hypertension; Circulatory System; Hypertension

• Registration Number: ISRCTN85520592
• Lead Sponsor: British Heart Foundation (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2002-03-28
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

1. Hypertension (requiring treatment according to British Hypertension Society [BHS] criteria)
2. Aldosterone/renin ratio >400
3. Either Systolic Blood Pressure (SBP) on spironolactone more than or equal to 20 mmHg, during previous open-label treatment or Plasma renin activity less than 0.2 pmol/ml/h and response to spironolactone not previously tested

Exclusion Criteria

Contraindications to study drugs

Study & Design

• Study Type: Interventional
• Study Design: Not specified