Investigating concurrent cognitive bias modification training and transcranial direct current stimulation in binge eating disorder

King's College London0 个研究点目标入组 66 人开始时间: 2018年5月18日最近更新: 2022年4月19日

适应症

试验速览

2019 Protocol article in https://pubmed.ncbi.nlm.nih.gov/31640997/ protocol (added 08/12/2020) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34460140/ (added 29/03/2022)

•1. Male and female community-dwelling adults between 18 and 70 years of age, who are overweight or obese according to WHO criteria (BMI =25 kg/m2)
•2. Full-syndrome or sub-threshold DSM-5 Binge Eating Disorder (BED) clinical criteria met

•1. Individuals with a significant/unstable medical or psychiatric disorders needing acute treatment in its own right (e.g., substance dependence), major psychiatric disorders (e.g., psychosis or acute suicidality)
•2. Individuals taking antidepressant medication who have not been on a stable dose for at least 2 weeks
•3. Individuals with a history of epileptic seizures, stroke, or brain injury, who have any implanted metal devices in the head, frequent or severe headaches or dizziness, or are pregnant or sexually active without using contraception (all contraindications to tDCS use are outlined in Brunoni et al. 2012)
•4. Individuals with severe abnormalities in a blood test during the 30 days prior to participation
•5. Individuals with allergies to any of the foods presented in the study
•6. Individuals who smoke >10 cigarettes per day
•7. Individuals who drink >3-4 units (men) or 2-3 units (women) of alcohol per day
•8. A tDCS safety questionnaire will also be administered and if considered not safe to deliver tDCS, individuals will subsequently be excluded on this basis

发起方