Bypass vs. Ecmo in Lung Transplantation (BELT)
Terminated
- Conditions
- Lung Transplant; Complications
- Registration Number
- NCT03021538
- Lead Sponsor
- The Cleveland Clinic
- Brief Summary
This study seeks to compare outcomes of 2 different methods of cardiopulmonary support during lung transplant surgeries.
- Detailed Description
This study will compare use of extracorporeal membrane oxygenation (ECMO) and heart-lung bypass (CPB) during lung transplant procedures and their short and long term outcomes.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 13
Inclusion Criteria
- The study population will be all patients requiring cardiopulmonary support while undergoing lung transplantation at our institution.
Exclusion Criteria
- Patients undergoing concomitant cardiac operations with indication for obligate use of cardiopulmonary bypass
- Patient with specific anatomy that require full cardiac decompression such as severe pulmonary hypertension or large heart that are shifted severely into the left chest
- Patients with high likelihood of significant pleural bleeding that will require returning the blood back into the cardiotomy reservoir
- Patients bridged to transplant with ECMO
- Cystic fibrosis/bronchiectasis/resistant infection patients where surgeon will need to remove both lungs prior to implantation
- Patients who the surgeon feels would be better served with CPB rather than ECMO- These patients will be entered into a registry and followed.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Need for Blood Transfusion 72 hours after surgery Number of pRBC transfusion that resulted due to postoperative bleeding
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Cleveland Clinic
🇺🇸Cleveland, Ohio, United States
Cleveland Clinic🇺🇸Cleveland, Ohio, United States