Studying respiratory infections and colonisation in children using daily minimally-invasive nasal sampling

Completed

• Conditions: respiratory tract infections; 10019815

• Registration Number: NL-OMON52240
• Lead Sponsor: niversitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 45

Inclusion Criteria

- Written informed consent obtained from both parents.
- Child aged 1 up to and including 5 (1-5) years of age attending day care,
peuterspeelzaal or school at least 2 (half) days a week.
- Parents ability and willingness to adhere to protocol-specified procedures,
including availability of a freezer at home to store samples.This does not
include donation of saliva by parents themselves, which is related to a
secondary endpoint.

Exclusion Criteria

- History of respiratory tract infections requiring hospitalization
- Current use of antibiotics, or antibiotics use in past four weeks
- Use of immune-altering medication (such as steroids, including inhaled
corticosteroid)
- No history of severe concomitant disease (severe congenital heart disease,
bronchopulmonary dysplasia, prematurity <32 weeks, cystic fibrosis, sickle cell
disease, congenital or acquired immunodeficiency disorders, cardiovascular
disease, neuromuscular disorders, oncology patients or major congenital
anomalies)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified