Anti-Müllerian Hormone is Not Predictive of Pregnancy in Donor Insemination Cycles in Non-infertile Women

Completed

• Conditions: Infertility
• Interventions: Diagnostic Test: Anti Mullerian Hormone Measurement

• Registration Number: NCT03160872
• Lead Sponsor: Institut Universitari Dexeus

Brief Summary

To evaluate if ovarian reserve (measured by means of anti-mullerian hormone -AMH- and antral follicle count -AFC-) can predict pregnancy in donor insemination cycles (dIUI) performed in non-infertile women.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-01-01
• Primary Completion: 2016-06-30
• Study Completion: 2016-12-15
• Status Verified: 2017-05
• Study First Submitted: 2017-05-18
• Study First Submitted QC: 2017-05-18
• Last Update Submitted: 2017-05-18
• Study First Posted: 2017-05-19
• Last Update Posted: 2017-05-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 143

Inclusion Criteria

• absence of male partner
• complete azoospermia or the presence of a genetic condition in the partner that made the couple opt for donor sperm
• absence of previous history of infertility.
• d ta on AMH and AFC assessment before the first dIUI cycle.

Exclusion Criteria

• previous history of infertility.

• Presence of any gynaecological condition that could impair the inseminations results:

  • endometriosis, hydrosalpinx,...

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Women who undergo donor sperm insemination	Anti Mullerian Hormone Measurement	Non infertile women who undergo donor sperm insemination cycle

Primary Outcome Measures

Name	Time	Method
Clinical Pregnancy	6 weeks after insemination procedure	Clinical Pregnancy evaluated by ultrasound with fetal heart beat

Secondary Outcome Measures

Name	Time	Method
Miscarriage rate	Evaluated until 15 weeks after insemination procedure	Number of clinical miscarriage after clinical pregnancy