A diminished ovarian reserve prediction cohort study
- Conditions
- Tracking of menstrual cycles and prediction of diminished ovarian reserve via wearable devicesUrological and Genital Diseases
- Registration Number
- ISRCTN27534184
- Lead Sponsor
- Obstetrics and Gynecology Hospital of Fudan University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- Female
- Target Recruitment
- 120
1. Aged 18-45 years old
2. AMH < 1.1 ng/mL
3. Menstruation within at least 6 months
3. Willing to participate in the follow-up and sign the informed consent
1. Menopause, pregnancy, lactation
2. Exogenous hormones within 3 months, history of ovarian surgery, planned exogenous hormone therapy
3. Suffering from other states or diseases that can affect heart rate, respiration, body temperature and sleep parameters: diseases of the cardiovascular system (hypertension, heart disease, arrhythmia, wearing a pacemaker, etc.), respiratory diseases, abnormalities of the thyroid function (hyperthyroidism/hypothyroidism, positive antibodies are not excluded), taking psychotropic medications
4. Severe systemic disease or any unstable disease or medical condition that, according to medical criteria, may jeopardize patient safety and his/her compliance with the requirements of the study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fertility measured using a serum anti-mullerian hormone (AMH) blood test at baseline, which is determined on the 2nd-4th day of menstruation for patients with a regular menstrual cycle, and on any day for those with irregular menstrual cycle
- Secondary Outcome Measures
Name Time Method Fertility measured using a basal hormone blood test (FSH, LH, E2, P, PRL, T, DHEA) at baseline and > 4 weeks, which is determined on the 2nd-4th day of menstruation for patients with regular menstrual cycle, and on any day for those with irregular menstrual cycle