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The Relationship between Periodontitis and Atherosclerosis in Patients with Acute Coronary Syndrome and The Impact for Periodontal Treatment to Atherosclerosis: A Prospective Observational Study

Not Applicable
Recruiting
Conditions
Coronary Artery Disease
Registration Number
JPRN-UMIN000038606
Lead Sponsor
Division of Cardiology, Department of Medicine, Nihon University School of Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
33
Inclusion Criteria

Not provided

Exclusion Criteria

1. Those who applied for refusal to participate in this study 2. Those who are difficult to conduct coronary angiography due to general condition, advanced dementia, etc. 3. Those who are deemed inappropriate by the principal investigator

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The severity of periodontitis and the complexity of coronary lesions(SYNTAX Score, ACC/AHA morphological classification), Correlation of degree of yellow plaque on coronary angioscopy, and The severity of periodontitis and the complexity of coronary lesions (SYNTAX Score, ACC/AHA morphological classification) in the chronic phase (after periodontal treatment or dental education if necessary), Rate of change in degree of yellow plaque on coronary angioscopy
Secondary Outcome Measures
NameTimeMethod
1. Relationship between periodontitis and degree of plaque on aortic angioscopy 2. Relationship between periodontitis and evaluation of arteriosclerotic changes by other tests (optical coherence tomography: OCT, coronary flow reserve: CFR, carotid echo, cardiac magnetic resonance imaging: MRI, etc.)
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