Platelet Rich Fibrin Versus Melatonin Around Dental Implants
Phase 2
Completed
- Conditions
- Patients With Missing Teeth
- Registration Number
- NCT05593731
- Lead Sponsor
- Misr University for Science and Technology
- Brief Summary
Dental implant is a dental treatment that allow oral rehabilitation for partial and fully edentulous patients. Osteointegration is the factor that control success s or failure of dental implant that can be improved by addition of different adjunctive biological materials. Platelets Rich fibrin plays a significant role in tissue regeneration and wound healing. Melatonin is biological hormone that secreted from pineal gland and played an important role in human growth.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 30
Inclusion Criteria
- good oral hygiene participants,
- free of any systemic diseases,
- Patients' age ranged from 20 to 40 years old.
- Patients who can complete surgery and the study protocol.
- Partially edentulous patients in the posterior mandibular region (at least a single-mandibular edentulous area) with periodontal health.
Exclusion Criteria
- patients who had parafunctional habits,
- current and former smokers, pregnant
- lactating women
- unmotivated patients
- patients with psychological problems
- patients who were not able to follow the treatment protocol -
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method gingival thickness 6 months
- Secondary Outcome Measures
Name Time Method marginal bone loss 6 months bone density 6 months
Trial Locations
- Locations (1)
Faculty of dentistry at MUST
🇪🇬Giza, Egypt
Faculty of dentistry at MUST🇪🇬Giza, Egypt