Evaluation of Local Delivered Platelet Rich Fibrin Versus Melatonin Gel on the Osseointegration of Dental Implant. A Randomized Controlled Clinical Trial

Misr University for Science and Technology1 site in 1 country30 target enrollmentDecember 10, 2021

ConditionsPatients With Missing Teeth

Overview

Phase: Phase 2
Intervention: Not specified
Conditions: Patients With Missing Teeth
Sponsor: Misr University for Science and Technology
Enrollment: 30
Locations: 1
Primary Endpoint: gingival thickness
Status: Completed
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Dental implant is a dental treatment that allow oral rehabilitation for partial and fully edentulous patients. Osteointegration is the factor that control success s or failure of dental implant that can be improved by addition of different adjunctive biological materials. Platelets Rich fibrin plays a significant role in tissue regeneration and wound healing. Melatonin is biological hormone that secreted from pineal gland and played an important role in human growth.

Registry

clinicaltrials.gov

Start Date

December 10, 2021

End Date

August 10, 2022

Last Updated

2 years ago

Study Type

Interventional

Study Design

Parallel

Sex

Female

Investigators

Sponsor

Misr University for Science and Technology

Responsible Party

Principal Investigator

Radwa Elsherif

lecturer of oral medicine, periodontology, oral diagnosis

Misr University for Science and Technology

Eligibility Criteria

Inclusion Criteria

•good oral hygiene participants,
•free of any systemic diseases,
•Patients' age ranged from 20 to 40 years old.
•Patients who can complete surgery and the study protocol.
•Partially edentulous patients in the posterior mandibular region (at least a single-mandibular edentulous area) with periodontal health.