Platelet-rich Factot in Implant Dentistry
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Osseointegrated Dental Implantation
- Sponsor
- Reza Tabrizi
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- implant loss
- Last Updated
- 11 years ago
Overview
Brief Summary
The main objective of this clinical trial study is to consider the effect of Platelet-Rich-Factor (PRF) on implant stability and marginal bone resorption around dental implants.
Detailed Description
Dental implants were placed in 30 subjects who have 1 or 2 missing teeth in both side of posterior mandible. Implants with a length of 11.5 and a diameter of 4.5 mm will be inserted in both sides. In one side PRF will be instilled after surface treatment with PRF before implant placement, while no PRF was added in other side to serve as control group. All implants will be followed with stability measurement by means of resonance frequency analysis at baseline, and every two weeks up to 3 months. Bone height was measured on medial \& distal side on standardized IOPA x-rays.
Investigators
Reza Tabrizi
Assistant professor of shahid beheshti university of medical sciences
Shiraz University of Medical Sciences
Eligibility Criteria
Inclusion Criteria
- •patients who have 1 or 2 missing teeth in both side of posterior mandible
- •adequate bone quantity and quality at the implant site
- •the implant sites with at least 3 months of healing after extraction,
- •patients well motivated for implant therapy and maintaining good oral hygiene
- •the implant sites with width and length to installation of an implant of 4.5 mm x 11.5 mm.
- •Patients who gave written informed consent
Exclusion Criteria
- •• medically compromised or patients taking any immunosuppressive drugs which may complicate the treatment outcome
- •infection around the implant site
- •history of bruxism/parafunctional habits
- •patients with history of any bleeding disorder or on anti-coagulant therapy.
- •pregnant patients
Outcomes
Primary Outcomes
implant loss
Time Frame: 6 months
During the osseointegration, if the implant lose his stability and if the patient have pain, the implant will be removed and the implant will be considered lost
Secondary Outcomes
- ISQ analysis(3 months)
- bone height (mm)(6 months)