Platelet-rich Factot in Implant Dentistry
试验速览
- 阶段
- 2 期
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- implant loss
研究概览
简要总结
The main objective of this clinical trial study is to consider the effect of Platelet-Rich-Factor (PRF) on implant stability and marginal bone resorption around dental implants.
详细描述
Dental implants were placed in 30 subjects who have 1 or 2 missing teeth in both side of posterior mandible. Implants with a length of 11.5 and a diameter of 4.5 mm will be inserted in both sides. In one side PRF will be instilled after surface treatment with PRF before implant placement, while no PRF was added in other side to serve as control group. All implants will be followed with stability measurement by means of resonance frequency analysis at baseline, and every two weeks up to 3 months. Bone height was measured on medial & distal side on standardized IOPA x-rays.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who have 1 or 2 missing teeth in both side of posterior mandible
- •adequate bone quantity and quality at the implant site
- •the implant sites with at least 3 months of healing after extraction,
- •patients well motivated for implant therapy and maintaining good oral hygiene
- •the implant sites with width and length to installation of an implant of 4.5 mm x 11.5 mm.
- •Patients who gave written informed consent
排除标准
- •• medically compromised or patients taking any immunosuppressive drugs which may complicate the treatment outcome
- •infection around the implant site
- •history of bruxism/parafunctional habits
- •patients with history of any bleeding disorder or on anti-coagulant therapy.
- •pregnant patients
结局指标
主要结局
implant loss
时间窗: 6 months
During the osseointegration, if the implant lose his stability and if the patient have pain, the implant will be removed and the implant will be considered lost
次要结局
- ISQ analysis(3 months)
- bone height (mm)(6 months)
研究者
Reza Tabrizi
Assistant professor of shahid beheshti university of medical sciences
Shiraz University of Medical Sciences