Social Cognition in Ageing and in Frontotemporal Lobar Degeneration

Not Applicable

• Conditions: Frontotemporal Lobar Degeneration; Aging

• Registration Number: NCT01962064
• Lead Sponsor: University Hospital, Caen

Brief Summary

The purpose of this study is to examine the age and the neurodegenerative disease effects on social cognition. Secondary goals are to better understand the relationships between different component of social cognition, executive functioning, and behavior and describing the neuronal substrates associated to the alteration of the social cognition in ageing and dementia.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-06
• Study First Submitted: 2013-09-03
• Status Verified: 2013-10
• Study First Submitted QC: 2013-10-10
• Last Update Submitted: 2013-10-10
• Study First Posted: 2013-10-14
• Last Update Posted: 2013-10-14
• Primary Completion: 2014-07
• Study Completion: 2014-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• All the participants

  • Age between 40 and 80 years
  • Minimum of 7 years of education
  • French native speaker

• Healthy subjects

  • Non pathological Dementia rating scale score

• Patients

  • Clinical diagnosis of frontotemporal lobar degeneration

Exclusion Criteria

• Chronic neurological disease
• Encephalitis
• Endocrinal disease
• Hepatic disease
• Case history of head injury with loss of consciousness of more than one hour
• Case history of stroke
• Case history of cancer during the five last years except squamous cell carcinomas
• Alcoholism or drug addiction
• Major psychiatric disorders according the Diagnostic and Statistical Manual of Mental Disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Primary Outcome Measures

Name	Time	Method
Social cognition scores	2 years	number of correct responses in a social cognition test

Trial Locations

Locations (1)

Inserm - EPHE - University of Caen U1077; 🇫🇷 Caen, France