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Comparison of Intubating Condition of the Mcgrath Videolaryngoscope With and Without Muscle Relaxant

Phase 1
Completed
Conditions
Muscle Relaxant
Interventions
Device: Videolaryngoscope
Registration Number
NCT02575716
Lead Sponsor
Prince of Songkla University
Brief Summary

The objective of this study was to evaluate intubating condition using the McGrath® VL Series 5, with and without muscle relaxant

Detailed Description

Thirty-four patients with ASA classification I-II, who required oroendotracheal tube intubation, were studied in this prospective, double-blinded, randomized, clinical trial. Anesthesia was induced using fentanyl 1.5 mcg/kg, xylocaine 1.5 mg/kg and propofol 3 mg/kg. Patients were randomly assigned to one of the two groups to receive either rocuronium 0.6 mg/kg or saline intravenously. The Mcgrath® VL intubation was initiated after 90s, when the patients were fully relaxed. The primary outcome was to compare tracheal intubating conditions between two groups. The secondary outcomes were the success rate in the first attempt intubation, time to intubation, the required propofol dose for intubation and anesthetic complications. Statistical analyses were performed using the R program version 2.14.2. The level of statistical significance was set at p \< 0.05.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
34
Inclusion Criteria
  • Age 18-65 years old.
  • ASA class I-II.
  • Elective surgery required general anesthesia with oroendotracheal intubation
Exclusion Criteria
  • Suspected or known difficult airway.
  • Patient with risk of aspiration with required of rapid sequence induction .
  • Plan remained intubation.
  • Allergic to drugs used in the study.
  • Renal or hepatic disease.

Study & Design

Study Type
INTERVENTIONAL
Study Design
FACTORIAL
Arm && Interventions
GroupInterventionDescription
Muscle relaxantVideolaryngoscopeIntubation with McGrath video laryngoscope after fentanyl 1.5 mcg/kg, xylocaine 1.5 mg/kg and propofol 3 mg/kg muscle relaxant use rocuronium 0.6 mg/kg
PlaceboVideolaryngoscopeIntubation with McGrath video laryngoscope after fentanyl 1.5 mcg/kg, xylocaine 1.5 mg/kg and propofol 3 mg/kg placebo use NSS 0.6 mg/kg
Primary Outcome Measures
NameTimeMethod
Intubating condition.one year

number of participants with 34 people

Secondary Outcome Measures
NameTimeMethod
Events during the intubation attempts occurred.one year
Success rate in the first attempt intubation.one year
Time to intubationOne year
The required propofol dose for intubation without muscle relaxant.one year

Trial Locations

Locations (1)

Department of anesthesiology

🇹🇭

Hatyai, Songkla, Thailand

Department of anesthesiology
🇹🇭Hatyai, Songkla, Thailand
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