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临床试验/NCT02575716
NCT02575716已完成1 期

Comparison of Intubating Condition of the Mcgrath Videolaryngoscope With and Without Muscle Relaxant

Prince of Songkla University2 个研究点 分布在 1 个国家目标入组 34 人开始时间: 2013年3月最近更新:
适应症

试验速览

阶段
1 期
状态
已完成
入组人数
34
试验地点
2
主要终点
Intubating condition.

研究概览

简要总结

The objective of this study was to evaluate intubating condition using the McGrath® VL Series 5, with and without muscle relaxant

详细描述

Thirty-four patients with ASA classification I-II, who required oroendotracheal tube intubation, were studied in this prospective, double-blinded, randomized, clinical trial. Anesthesia was induced using fentanyl 1.5 mcg/kg, xylocaine 1.5 mg/kg and propofol 3 mg/kg. Patients were randomly assigned to one of the two groups to receive either rocuronium 0.6 mg/kg or saline intravenously. The Mcgrath® VL intubation was initiated after 90s, when the patients were fully relaxed. The primary outcome was to compare tracheal intubating conditions between two groups. The secondary outcomes were the success rate in the first attempt intubation, time to intubation, the required propofol dose for intubation and anesthetic complications. Statistical analyses were performed using the R program version 2.14.2. The level of statistical significance was set at p < 0.05.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Treatment
盲法
Triple (Participant, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age 18-65 years old.
  • ASA class I-II.
  • Elective surgery required general anesthesia with oroendotracheal intubation

排除标准

  • Suspected or known difficult airway.
  • Patient with risk of aspiration with required of rapid sequence induction .
  • Plan remained intubation.
  • Allergic to drugs used in the study.
  • Renal or hepatic disease.

结局指标

主要结局

Intubating condition.

时间窗: one year

number of participants with 34 people

次要结局

  • Events during the intubation attempts occurred.(one year)
  • Success rate in the first attempt intubation.(one year)
  • Time to intubation(One year)
  • The required propofol dose for intubation without muscle relaxant.(one year)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Piyaporn Vasinanukorn

Dr.

Prince of Songkla University

研究点 (2)

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