Analgesic Effect of Etoricoxib (ARCOXIA®) 120MG During Retinal Laser Photocoagulation

Not Applicable

Completed

• Conditions: Proliferative Diabetic Retinopathy
• Interventions: Drug: placebo (Control Group); Drug: Etoricoxib (Treatment Group)

• Registration Number: NCT00529594
• Lead Sponsor: University of Sao Paulo

Brief Summary

The study wants to show if the medication etoricoxib 120 mg have reduces the patients pain during the laser photocoagulation, for diabetic retinopathy.

Detailed Description

To do so we compare two group of patients, randomized 1:1, one use the medication(etoricoxib) and other use placebo and they quantify the pain using the Pain visual analogue scale

Study Timeline

• Study Start: 2006-08
• Study Completion: 2006-11
• Status Verified: 2007-03
• Study First Submitted: 2007-09-13
• Study First Submitted QC: 2007-09-13
• Last Update Submitted: 2007-09-13
• Study First Posted: 2007-09-14
• Last Update Posted: 2007-09-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

• Patients with diabetic retinopathy that needs laser photocoagulation for the first time

Exclusion Criteria

• Younger than 17
• Signs and symptoms of liver dysfunction or abnormal liver function tests
• Gastrointestinal diseases
• Pregnant women
• Edema
• Pre-existing cardiac insufficiency

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Control Group	placebo (Control Group)	Patients who received placebo
Treatment Group	Etoricoxib (Treatment Group)	Patients who received etoricoxib 120 mg

Primary Outcome Measures

Name	Time	Method
The group taking the etoricoxib feel less pain then the group taking placebo	After each laser session

Trial Locations

Locations (1)

Clinica Oftalmologica do Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo; 🇧🇷 São Paulo, SP, Brazil