Effectiveness of Etoricoxib 120 mg in Pain Relief during IUD Insertion; A Randomized, Double-blinded, Placebo controlled, Clinical Trial

Phase 4

• Conditions: Effectiveness of Etoricoxib 120 mg in Pain Relief during IUD Insertion; A Randomized, Double- blinded, Placebo controlled, Clinical Trial; Preemptive Analgesia; Etoricoxib; Arcoxia; Coxib

• Registration Number: TCTR20160811002
• Lead Sponsor: one

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-08-11
• Study Completion: 2017-02-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Enrolling by invitation
• Sex: Female
• Target Recruitment: 130

Inclusion Criteria

- Women who desired for IUD insertion
- Aged of 18 to 45 years old
- BMI between 18.5 †30.0 kg/m2
- Agree to join the research

Exclusion Criteria

Women who contraindicated for IUD used
- Could not be ruled out pregnancy
- Had some degrees of physiological or anatomical distortion of uterus
- Recent pelvic inflammatory disease or prone to be
- Had confronted unexplained bleeding from genitalia
- Wilson’s disease
- Allergy to chemical agents in IUD
Contraindicated to etoricoxib used
- Allergy to chemical agents in the drug
- History of asthma
- Allergy to aspirin or others NSAIDs
- Heart failure
- Poor controlled high blood pressure (>140/90mmHg)
- History of ischemic heart, arteriole-venous disease, cerebrovascular disease and who had history of surgery of all above
- Used to have any medication which related to liver function

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the efficacy of Etoricoxib 120mg with placebo during IUD contraceptives insertion 1hr before insertion,immediately after insertion, and 15minutes after insertion Visual analog scales,To compare the efficacy of Etoricoxib 120mg with placebo during IUD contraceptives insertion 1hr before insertion,immediately after insertion, and 15minutes after insertion Visual analog scales

Secondary Outcome Measures

Name	Time	Method
Factors related to the pain during insertion, side effects of etoricoxib as study drugs Before and after study drug intake Questionaires