Skip to main content
MedPathMedPath Home
Clinical Trials/EUCTR2011-000644-16-EE
EUCTR2011-000644-16-EE
Active, not recruiting
Not Applicable

High volume haemodiafiltration in treatment of severe sepsis -- impact on pharmacokinetics of doripenem and piperacillin tazobactam and inflammatory response

niversity of Tartu, Clinic of Anaesthesiology and Intensive Care0 sites30 target enrollmentMarch 24, 2011
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
Conditionsadult intensive care patient with severe sepsis or septic shock and acute renal failure requiring renal replacement therapyMedDRA version: 13.1Level: PTClassification code 10040047Term: SepsisSystem Organ Class: 10021881 - Infections and infestationsMedDRA version: 13.1Level: LLTClassification code 10001041Term: Acute renal failureSystem Organ Class: 10038359 - Renal and urinary disordersMedDRA version: 13.1Level: PTClassification code 10053879Term: Sepsis syndromeSystem Organ Class: 10021881 - Infections and infestations
DrugsDoribaxTazocin

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
adult intensive care patient with severe sepsis or septic shock and acute renal failure requiring renal replacement therapy
Sponsor
niversity of Tartu, Clinic of Anaesthesiology and Intensive Care
Enrollment
30
Status
Active, not recruiting
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
March 24, 2011
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional clinical trial of medicinal product
Sex
All

Investigators

Sponsor
niversity of Tartu, Clinic of Anaesthesiology and Intensive Care

Eligibility Criteria

Inclusion Criteria

  • •age \>\= 18 years
  • •severe sepsis or septic shock as defined by the ACCP/SCC Consensus Conference
  • •acute renal failure requiring renal replacement therapy
  • •written informed consent signed by legal representative
  • •Are the trial subjects under 18? no
  • •Number of subjects for this age range:
  • •F.1\.2 Adults (18\-64 years) yes
  • •F.1\.2\.1 Number of subjects for this age range
  • •F.1\.3 Elderly (\>\=65 years) yes
  • •F.1\.3\.1 Number of subjects for this age range

Exclusion Criteria

  • •contraindication for study drug use
  • •life expectancy less than 6 h

Outcomes

Primary Outcomes

Not specified

Similar Trials

Completed
Not Applicable
High cut-off Continuous venovenous haemodialysis (CVVHD) to improve haemodynamic stability and Organ function scores in patients treated for acute renal failure after Systemic inflammatory response Syndrome (SIRS)/septic shockAcute renal failure after SIRS/septic shockUrological and Genital DiseasesRenal failure
ISRCTN77656437Gambro Dialysatoren GmbH (Germany)120
Completed
Not Applicable
Outcomes of intraoperative haemofiltration for patients with impaired kidney function undergoing coronary artery bypass graft surgeryPreoperative renal impairmentcoronary heart diseasecardiac artery bypass graft surgeryUrological and Genital Diseases
ISRCTN49513454iverpool Heart & Chest Hospital NHS Foundation Trust (UK)60
Completed
Not Applicable
To Assess the Effect of HDF Versus High Flux Dialysis on Free Light Chains and Cumulative Albumin Loss, in End Stage Renal Disease Patients.End Stage Renal DiseaseHemodiafiltrationHemodialysis
NCT04747067Ain Shams University25
Recruiting
Not Applicable
FINESSE Trial – Filtration In the Neuropathy of End Stage kidney disease Symptom Evolutio
ACTRN12609000615280Statewide Renal Services120
Completed
Not Applicable
Effect of High volumeHemodiafiltration on Lung OxygenationHaemofiltrationLung MechanicsSeptic Patients
NCT03853005Assiut University40