tDCS over the dorsolateral prefrontal cortex improves pain, anxiety and functionality in primary dysmenorrhea: a randomized sham-controlled trial.

Not Applicable

• Conditions: Dysmenorrhea; Chronic Pain; colic; pelvic pain; C23.550.568.750; C23.888.592.612.274; C16.614.166; C23.888.592.612.944

• Registration Number: RBR-77z6q8
• Lead Sponsor: niversidade Federal do Rio Grande do Norte

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-07-04
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Aged from 18 to 40 years; regular menstrual cycle from 28 to 32 days; without breastfeeding; not history of brain surgery; not tumor hystory; not history of chronicle genitourinary infectious; without history of alcohol or drug abuse.

Exclusion Criteria

Mean pain score of at least 3 on the Numeric Rating Scale (NRS) during the menstrual cycle preceding the evaluation; patients presenting history of dizziness or epileptic disease; pregnancy; metal implants in the head.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain: measured using the numerical pain scale (NRS). Analyses were made using NRS at the first, second and third days over the first menstrual cycle (without tDCS) and in the first, second and third days over the second menstrual cycle (with tDCS).

Secondary Outcome Measures

Name	Time	Method
The patients' mood was evaluated through the Positive and Negative Affect Scale (PANAS). The higher the scores of each, the higher the representativeness of the negative / positive mood for each individual.;Anxiety: measured through the Hamilton anxiety scale. Score varies from 0-4 according to the intensity of the symptoms, in which 0 = absent; 2 = slight; 3 = average; 4 = maximum. The total score varies from 0 to 56 and the higher the score, the worse the anxiety state of the interviewee.;Functionality: measured by the submaximal functional capacity, measured with the 6-minute walk test (6MWT). For the analysis of the present study will be considered the positive variation of the distance before and after the CTEF, being considered the increase in meters as an improvement in functional capacity.