A Clinical Trial to Evaluate the Analgesic Efficacy and Safety of Nefopam(Acupan®) Compared to Oxycodone (Oxynorm®) in Postoperative Intravenous Patient-Controlled Analgesia of Patients Undergoing General Surgery

Not Applicable

Recruiting

• Conditions: Symptoms, signs and abnormal clinical and laboratory findings, NEC

• Registration Number: KCT0003896
• Lead Sponsor: Asan Medical Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 May 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 246

Inclusion Criteria

Patients undergoing general anesthesia under laparoscopic gastrointestinal or colorectal surgery
- Patients who applied for postoperative intravenous patient-controlled analgesia
- American Society of Anesthesiologists Physical Status 1, 2, and 3

Exclusion Criteria

- Patients taking pain medication preoperatively
- Patients who are anaphylactic to nefopam or oxycodone
- Patients with estimated glomerular filtration rate <60 ml / min / 1.73 m2
- Patients with a history of epilepsy
- Patients with a history of ischemic heart disease
- Patients taking monoamine oxidase inhibitor
- Patients with walking disorders
- Patients who can not press the analgesic administration button themselves for pain relief when there is postoperative pain due to impaired cognitive function or comprehension.

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
postoperative 24 hour visual analgoue scale value for pain

Secondary Outcome Measures

Name	Time	Method
postoperative 6 hour visual analgoue scale value for pain;analgesics dose;Rhodes Index of Nausea, Vomiting, and Retching;Sedation scale;respiratory depression;Excessive sweating