Comparison of surgical stress response in standard pressure pneumoperitoneum versus isobaric pneumoperitoneum (gasless) in patients undergoing Laparoscopic cholecystectomy: A Randomized Controlled Study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Percentage change in hs-CRP in Laparoscopic Cholecystectomy with standard pressure pneumoperitoneum and isobaric pneumoperitoneum(gasless) at preoperative (8 am morning of surgery), immediate postoperative (during skin closure), and postoperative (2 hours and 24 hours after surgery) period.
研究概览
简要总结
To compare surgical stress response in standard pressure pneumoperitoneum versus isobaric pneumoperitoneum (gasless) in patients undergoing laparoscopic cholecystectomy in terms of hs-CRP.
PRIMARY OBJECTIVES: To compare surgical stress response in terms of hs-CRP in both groups.
SECONDARY OBJECTIVES:
To compare ACTH, Cortisol, IL-6, Neutrophil:Lymphocyte ratio in both groups.
To compare postoperative pain and duration of hospital stay in both groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •18-65 years.
排除标准
- •Pregnancy and lactation.
- •Known case of Rheumatoid Arthritis, Inflammatory Bowel Disease.
- •BMI above 30 kg/m
- •Empyema Gallbladder.
结局指标
主要结局
Percentage change in hs-CRP in Laparoscopic Cholecystectomy with standard pressure pneumoperitoneum and isobaric pneumoperitoneum(gasless) at preoperative (8 am morning of surgery), immediate postoperative (during skin closure), and postoperative (2 hours and 24 hours after surgery) period.
时间窗: Preoperative (8 am morning of surgery), immediate postoperative (during skin closure), and postoperative (2 hours and 24 hours after surgery) period.
次要结局
- Comparison of ACTH, Cortisol, IL-6, Neutrophil:Lymphocyte ratio(Early morning of surgery, 2 hours and 24 hours after surgery)
研究者
Soukat Ali Khan
Maulana Azad medical College