Impact Of Supervised 12-Week-Combined Physical Training In Heart Failure Patients: A Randomized Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Heart Failure Patients
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
- Enrollment
- 28
- Primary Endpoint
- Questionnaire about quality of life
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
Purpose: Physical exercise exerts favorable impact on functional capacity (FC) and quality of life (QL) in patients with heart failure (HF). It is believed that the combined aerobic and resistance physical training (CPT) supervised by physical educator is better than only prescription of unsupervised exercise. The aim of this study is to compare the effects of a CPT program on the FC and QL of HF patients with reduced ejection fraction (HFREF) with the practice medical routine prescription of regular physical activity and correlate these findings with clinical and echocardiographic variables.
Methods: A longitudinal prospective study included 28 consecutive HFREF patients randomly divided in two age- and gender- matched groups: Trained Group (TG, n = 17), patients undergoing 12 weeks of supervised CPT and Non Trained Group (NTG, n = 11), patients receiving only medical prescription to practice regular physical exercise. All patients were submitted to clinical evaluation, transthoracic echocardiography, Cooper walk test and QL questionnaire before and after the study protocol. Student t test or Mann-Whitney test were performed for groups comparison and correlation tests for the same group variable associations.
Investigators
Tainá Fabri
Master's degree
Universidade Estadual Paulista Júlio de Mesquita Filho
Eligibility Criteria
Inclusion Criteria
- •Patients with heart failure with LVEF \<50%;
- •Patients with optimized drug therapy;
- •Age over 18 years.
Exclusion Criteria
- •Heart failure NYHA class IV and/or Stage D;
- •Decompensated HF in the last three months;
- •Atrial fibrillation and/or implantable device at the moment of inclusion;
- •Patients with chronic obstructive pulmonary disease (COPD);
- •Patients with biomechanical limitations of physical activity.
Outcomes
Primary Outcomes
Questionnaire about quality of life
Time Frame: up to 12 weeks of research
Cardiorespiratory evaluation (VO2 in Mets)
Time Frame: up to 12 weeks of research
Morphological echocardiographic variables (mm)
Time Frame: up to 12 weeks of research
Sistolic Function echocardiographic variables (Percentage)
Time Frame: up to 12 weeks of research
Diastolic Function echocardiographic variables (cm/s)
Time Frame: up to 12 weeks of research
Secondary Outcomes
- Anthropometric measurements (cm)(up to 12 weeks of research)
- Body composition (%fat percentage)(up to 12 weeks of research)
- Presence of comorbidities(up to 12 weeks of research)
- Blood pressure measurement (mmHg)(up to 12 weeks of research)