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12-Week-Combined Physical Training In Heart Failure Patients

Not Applicable
Completed
Conditions
Heart Failure Patients
Interventions
Other: Combined aerobic and resistance physical training program
Registration Number
NCT02571270
Lead Sponsor
Universidade Estadual Paulista Júlio de Mesquita Filho
Brief Summary

Purpose: Physical exercise exerts favorable impact on functional capacity (FC) and quality of life (QL) in patients with heart failure (HF). It is believed that the combined aerobic and resistance physical training (CPT) supervised by physical educator is better than only prescription of unsupervised exercise. The aim of this study is to compare the effects of a CPT program on the FC and QL of HF patients with reduced ejection fraction (HFREF) with the practice medical routine prescription of regular physical activity and correlate these findings with clinical and echocardiographic variables.

Methods: A longitudinal prospective study included 28 consecutive HFREF patients randomly divided in two age- and gender- matched groups: Trained Group (TG, n = 17), patients undergoing 12 weeks of supervised CPT and Non Trained Group (NTG, n = 11), patients receiving only medical prescription to practice regular physical exercise. All patients were submitted to clinical evaluation, transthoracic echocardiography, Cooper walk test and QL questionnaire before and after the study protocol. Student t test or Mann-Whitney test were performed for groups comparison and correlation tests for the same group variable associations.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
28
Inclusion Criteria
  • Patients with heart failure with LVEF <50%;
  • Patients with optimized drug therapy;
  • Age over 18 years.
Exclusion Criteria
  • Heart failure NYHA class IV and/or Stage D;
  • Decompensated HF in the last three months;
  • Atrial fibrillation and/or implantable device at the moment of inclusion;
  • Patients with chronic obstructive pulmonary disease (COPD);
  • Patients with biomechanical limitations of physical activity.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Lifestyle counselingCombined aerobic and resistance physical training programLifestyle counseling helps patients to have better self-care.
Active lifestyleCombined aerobic and resistance physical training programActive lifestyle involves nutritional education, physical activity and active recreation.
survivalCombined aerobic and resistance physical training programThe survival of patients with heart failure may increase with exercise training.
secondary preventionCombined aerobic and resistance physical training programSecondary prevention it is essential to prevent a new unfavorable event.
Primary Outcome Measures
NameTimeMethod
Questionnaire about quality of lifeup to 12 weeks of research
Cardiorespiratory evaluation (VO2 in Mets)up to 12 weeks of research
Morphological echocardiographic variables (mm)up to 12 weeks of research
Sistolic Function echocardiographic variables (Percentage)up to 12 weeks of research
Diastolic Function echocardiographic variables (cm/s)up to 12 weeks of research
Secondary Outcome Measures
NameTimeMethod
Anthropometric measurements (cm)up to 12 weeks of research
Body composition (%fat percentage)up to 12 weeks of research
Presence of comorbiditiesup to 12 weeks of research
Blood pressure measurement (mmHg)up to 12 weeks of research
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