NCT00477997已完成不适用
The Effect of a Physiological Bolus of Growth Hormone (GH) on Insulin Signaling Pathways in Muscle Tissue From Healthy Adults
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 8
- 试验地点
- 1
- 主要终点
- PI3-kinase activity i muscle tissue
研究概览
简要总结
The purpose of this study is to examine the effects of a physiological bolus of growth hormone on insulin signaling pathways in muscle tissue in healthy lean men.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Age between 18 and 30 years
排除标准
- •Known present disease including diabetes mellitus
- •BMI > 26
- •Uses any medication
- •Consumes > 21 units of alcohol per week
研究组 & 干预措施
1
Placebo Comparator
Saline bolus + OGTT
干预措施: Physiological Bolus of Growth Hormone (Device)
2
Other
GH-bolus and OGTT
干预措施: Physiological Bolus of Growth Hormone (Device)
3
Other
GH-bolus
干预措施: Physiological Bolus of Growth Hormone (Device)
结局指标
主要结局
PI3-kinase activity i muscle tissue
时间窗: 2 hours
次要结局
- Growth Hormone Signaling Proteins in Muscle Tissue and other Insulin Signaling Proteins in Muscle Tissue(2 hours)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
1 期
Effects of Growth Hormone on the Nitric Oxide PathwayCardiovascular DiseaseNCT00470002Hannover Medical School16
已完成
不适用
Effect of Growth Hormone (GH) on Cardiac Echos in GH Deficient Patients After Acromegaly TreatmentAcromegalyNCT01302652Massachusetts General Hospital20
已完成
2 期
Influence of exogenous growth hormone administration on circulating levels of Klotho in healthy and chronic kidney disease subjects10029149renal insufficiencyChronic kidney diseaseNL-OMON40366Vrije Universiteit Medisch Centrum20
进行中（未招募）
不适用
Influence of growth hormone administered subcutaneously on circulating Klotho levels in healthy subjects and subjects with renal failure.Cardiovascular disease in chronic kidney diseaseEUCTR2013-003354-24-NLVrij Universiteit Medical Center
已完成
不适用
Influence of exogenous growth hormone administration on circulating levels of Klotho in paediatric patients with isolated growth hormone deficiency.Klotho levels in isolated growth hormone deficiency10021112NL-OMON44245Vrije Universiteit Medisch Centrum20