Evaluation of effects of pomegeranate seed oil on lipid profiles, apolipoproteines and body composition in subjects with low HDL-C concentrations
- Conditions
- low HDL-C concentrations.Disorders of lipoprotein metabolism and other lipidaemias
- Registration Number
- IRCT201107201640N5
- Lead Sponsor
- Research Institute for Endocrine Science, Shaheed Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 150
willingness to cooperate; ages 20-70 years; those with 35= BMI (kg/m2) =25; having levels of HDL-C <40mgr/dl in the last 12 months; Who are placed in stage I and stage II on TLC, according to NCEP ATP III criteria; Diabetic people not used Glitazones and insulin or consume constantly oral diabetes medications for at least three months Even if taking anti-lipid medications (statins and fibers); Lack of breastfeeding and pregnancy; Those who have had less than 5 Kg in body weight in the last 3 months; Not having any thyroid disorders and kidney failure; Lack of any severe mental illness; Not having cancer in the past five years; Lack of peptic ulcer disease; No smoking and alcohol; Not using drugs affecting lipid profile such as corticosteroids, cyclosporine, propranolol and glucocorticoid. Exclusion criteria: weight loss >10Kg during the study, Diagnosis of any of the diseases mentioned in inclusion criteria, during the study; Patient's lack of cooperation in each of the stages studied.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ow HDL-C. Timepoint: baseline and end of weeks 2, 4, 8 and 12. Method of measurement: Enzymatic colorimetric method and sediment specific.
- Secondary Outcome Measures
Name Time Method Body weight. Timepoint: at the start and end of the 12 weeks study. Method of measurement: anthropometric measurements.;Blood pressure. Timepoint: at the start and end of the 12 weeks study. Method of measurement: blood pressure measurement.