Effect of a preload on postprandial glycaemic response and satiety.

Not Applicable

• Conditions: Dysglycaemia; Diet and Nutrition - Other diet and nutrition disorders; Metabolic and Endocrine - Metabolic disorders

• Registration Number: ACTRN12616000771459
• Lead Sponsor: niversity of Otago

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-06-14
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Healthy adults of Chinese ethnicity

Exclusion Criteria

Inability to speak English; self-reported disease of the digestive system (coeliac, Crohn’s); having had gastrointestinal surgical procedures; an allergy to kiwifruit; and pregnancy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood glucose response[Blood glucose concentrations will be measured at baseline (before eating) and at 15, 30, 45, 60, 75, 90, 120, and 150 minutes thereafter];Satiety will be assessed using a visual analogue scale (reference Flint et al. Reproducibility, power and validity of visual analogue scales in assessment of appetite sensations in single test meal studies. Int J Obes 2000;24:38-48). [Satiety will be measured via a validated questionnaire at baseline (before eating) and at 15, 30, 45, 60, 75, 90, 120, and 150 minute thereafter];Circulating blood vitamin C concentration[The vitamin C concentration will be measured at baseline (before eating) and at 15, 30, 45, 60, 75, 90, 120, and 150 minutes thereafter]

Secondary Outcome Measures

Name	Time	Method
Blood insulin concentration[Blood insulin will be measured at baseline (before eating) and at 15, 30, 60, 90, 120, and 150 minutes thereafter];Ghrelin concentration using a Milliplex assay[We will measure ghrelin concentration in blood samples at baseline (before eating) and at 15, 30, 60, 90, 120, and 150 minutes thereafter];Glucagon-like peptide-1 (GLP-1) concentration using a Milliplex assay[We will measure GLP-1 concentration in blood samples at baseline (before eating) and at 15, 30, 60, 90, 120, and 150 minutes thereafter];Interleukin-6 (IL-6) concentration using a Milliplex assay[We will measure Interleukin-6 (IL-6) concentration in blood samples at baseline (before eating) and at 15, 30, 60, 90, 120, and 150 minutes thereafter]