Proteomics analysis of cerebrospinal fluid to investigate brain involvement in pre-eclampsia

Completed

• Conditions: neurologische aandoeningen tijdens de zwangerschap; pre-eclampsia; 10026908

• Registration Number: NL-OMON43723
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

Non pregnant women of 18 year and older

Exclusion Criteria

Pregnant during inclusion
Pre-eclampsia in history
Auto-immune disorders
Oral corticosteroid use
Hemoglobinopathy or clotting disorder
Chronic hypertension or proteinuria
Kidney disorders
Neurologic disorder

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The present research aims to obtain a control group of women who are not<br /><br>pregnant and do not have pre-eclampsia.<br /><br>The outcome measure of the previous research project was pre-eclampsia: a blood<br /><br>pressure * 140 mmHg (systolic) and * 90mmHg (diastolic) during at least two<br /><br>measurements after 20 weeks of pregnancy in combination with proteinuria (* 300<br /><br>mg / 24 hours or protein / creatinine ratio of * 30 mg / mmol).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable</p><br>