The effects of mild prematurity on asthma-like symptoms, Lung Clearance Index and exercise performance at the age of 12.

Completed

• Conditions: prematurity; preterm birth; 10028971

• Registration Number: NL-OMON41101
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 80

Inclusion Criteria

Research group
- Born between 32 and 35 +6 weeks of gestation
- From one of the three northern provinces (Drenthe, Groningen and Friesland)
Control group
- Born after 38 weeks gestation
- From one of the three northern provinces (Drenthe, Groningen and Friesland)

Exclusion Criteria

Research group
- Duration of pregnancy not precisely determined by ultrasound during pregnancy
- Physical inability to carry out ergometrie test
- Birth Defects
- Illness or fever at the time of measurement
Control group:
- Duration of pregnancy is not exactly determined by ultrasound
- Physical inability to carry out ergometrie test
- Birth Defects
- Use of bronchodilators
- Illness or fever at the time of measurement

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Spirometry FVC, FEV1, FEV1/FVC, FEF25, FEF50, FEF75,<br /><br>PEF<br /><br>Ergometire Heart rate, respiratory rate, maximum load,<br /><br>VO2rust, maximum respiratory rate, VT, VTmax, VEmax,<br /><br>ventilatory reserve, VO2 at the<br /><br>anaerobic threshold (AD), VO2max, AD, AD/VO2, *VO2/*WR, respiratory exchange<br /><br>ratio,<br /><br>Borg score<br /><br>LCI LCI</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>respiratory symptoms due to questionnaire</p><br>