NL-OMON40712已完成不适用
The role of (micro)vasculature and angiogenesis in inflammatory diseases of the human skin - (micro)vasculature and angiogenesis in inflammatory skin diseases
Dermatologie0 个研究点目标入组 60 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Patients must meet the following criteria:
- •- Adults older than 18 years of age
- •- All patients have tot have chronique plaque psoriasis (i.e. psoriasis vulgaris)
- •- Patients must be willing to give a written informed consent
- •- Patients must be able to adhere to the visit schedule
- •- Applicable in fifty patients; The doctor and the patient decided that the best treatment option was photo therapy, clobetasol 17-proprionate, dithranol or anti-TNF treatment;Criteria voor vrijwilligers:
- •- Adults older than 18 years of age
- •- Volunteers must be willing to give written informed consent
- •- Volunteers must be able to adhere to the visit schedule
排除标准
- •Patients will be excluded from this study when any of the following criteria listed below are met:
- •- Children or adolescents younger than 18 years of age
- •- Patients with relevant co-morbidities
- •- Patients with another subtype of psoriasis than psoriasis vulgaris
- •- Patients with a history of signs of other (inflammatory) skin diseases, for example atopic dermatitis
- •- Patients who use medication with inhibitory effects on angiogenesis (for example Thalidomide (Softanon®), Sunitinib (Sutent®), COX-2 inhibitors as NSAIDs)
- •- Patients with co-morbidity that positively or negatively affects angiogenesis (such as microangiopathy and/or peripheral vascular disease in diabetics, smokers, etc)
- •- Use of anti-psoriatic medication before inclusion:
- •- Topical medication in the last 7 days
- •- Systemic medication or photo therapy within the last 4 weeks
- •- Patients with multiple (superficial) wounds and excoriations
- •- Patients with contra-indications for any kind of psoriatic treatment;Exclusion criteria for Healthy volunteers:
- •- Children or adolescents younger than 18 years of age
- •- Volunteers with relevant co-morbidities
- •- Volunteers with a history or signs of other (inflammatory) skin diseases, for example atopic dermatitis and psoriasis
- •- Volunteers who use medication with inhibitory effects on angiogenesis (for example Thalidomide (Softanon®), Sunitinib (Sutent®), COX-2 inhibitors as NSAIDs)
- •- Volunteers with co-morbidity that positively or negatively affects angiogenesis (such as micro-angiopathy and/or peripheral vascular disease in diabetics, smokers, etc)
- •- Volunteers with multiple (superficial) wounds and excoriations
研究者
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