IL-38 Evaluation as a Biomarker in Pediatric Asthma

Not Applicable

Completed

• Conditions: Bronchial Asthma
• Interventions: Diagnostic Test: Il-38 serum level

• Registration Number: NCT05366491
• Lead Sponsor: Cairo University

Brief Summary

The aim of this study is to investigate the associations between serum IL-38 levels and different variables of asthma in children such as laboratory variables, pulmonary function test results, the diagnosis of asthma, and in correlation with disease severity.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-08-01
• Primary Completion: 2021-01-12
• Study Completion: 2021-04-15
• Status Verified: 2022-05
• Study First Submitted: 2022-05-05
• Study First Submitted QC: 2022-05-05
• Last Update Submitted: 2022-05-08
• Study First Posted: 2022-05-09
• Last Update Posted: 2022-05-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 103

Inclusion Criteria

• patients fulfilled the criteria of the Global Initiative for Asthma (GINA)
• Age group:6-14 years

Exclusion Criteria

• Malignancy
• Chronic inflammatory diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
bronchial asthma patients	Il-38 serum level	patients diagnosed with bronchial asthma
healthy controls	Il-38 serum level	healthy subjects with age and sex matched to bronchial asthma patients

Primary Outcome Measures

Name	Time	Method
serum IL-38 levels	within 6 months	Measurement of Interleukin 38 in sera of all study subjects by ELISA

Trial Locations

Locations (1)

Asmaa Kamal; 🇪🇬 Cairo, Egypt