Prospective Evaluation of Disparities in Provision of Allogeneic Transplantation
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,200
- 试验地点
- 1
- 主要终点
- Patient Ancestry Questionnaire
研究概览
简要总结
To look at the effect of a recipient's ancestry and socio-economic status on their choice of bone marrow transplantation donor cells and their chance of receiving genetically similar (allogeneic) bone marrow cells versus cells that are not genetically similar (allograft).
详细描述
Primary Objectives To prospectively evaluate graft options and choice of donor by patient ancestry and SES for allograft candidates at MDACC.
Secondary Objectives
- To prospectively evaluate time to transplant for allograft candidates at MDACC.
- To evaluate treatment-related mortality for allograft candidates at MDACC.
- To assess overall survival for allograft candidates at MDACC.
- To prospectively evaluate receipt of preferred unrelated donor for allograft recipients at MDACC.
- To evaluate receipt of an optimal graft for allograft recipients at MDACC.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •≥ 18 years of age.
- •Candidate for allogeneic transplantation
排除标准
- •1) Allogeneic stem cell transplantation not medically indicated.
研究组 & 干预措施
Prospective evaluation
Participants are expected to be in this research study for up to 2 years after the participants bone marrow transplantation. However, your active participation will only last 1 day, when you sign the consent form and complete a questionnaire about your demographic information and ancestry (family ethnicity). For the rest of the study, information about the participants medical history, choice of bone marrow donor, and health outcomes will be collected from your medical record.
干预措施: Patient Ancestry Questionnaires (Behavioral)
结局指标
主要结局
Patient Ancestry Questionnaire
时间窗: Through study completion; an average of 1 year.
次要结局
未报告次要终点