A comparative study of safety and efficacy of a local anaesthesia combined with two different adjuvants ; given as USG guided nerve block, in patientsundergoing upper limb orthopaedic surgery.â€

Completed

Conditions: Unspecified fracture of forearm,

Registration Number: CTRI/2020/06/025823

Lead Sponsor: Dr Sampurnanand Medical College

Brief Summary: Post-operatively regional anaesthesia is of great value to treat pain following surgery and to minimize the use of opiods. Long acting local anaesthetic like Ropivacaine used for regional anaesthesia. Addition of an adjuvant to local anaesthetic can further have the advantage of prolonging the duration of block and post operative analgesia. In recent years supraclavicular brachial plexus block has gained popularity with addition of various adjuvant to anaesthetic solution. Present study we have taken two alpha receptor agonist Clonidin and Dexmeditomidine as adjuvant to Ropivacaine. We aim to discover which is more superior regarding safety and efficacy.

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 50

Inclusion Criteria

ASA I & II of body weight 30 to 80 kg, undergoing upperlimb orthopaedic surgery of less than two hours duration.
Free from any associated chronic systemic illness.

Exclusion Criteria

Uncooperative patient Pregnant or lactating mother Neurological deficit in operative limb with chronic pain or on long term analgesics Patient having hypersensitivity or contraindication to Ropivacaine/ Dexmedetomidine/ Clonidine Local pathology at the site of injection All disability limiting the performance of block.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. To compare the duration of analgesia,onset of sensory and motor block of	Assessment of block quality by calculation of composite score of bromage scale and duration of analgesia was recorded by patient response.
0.5% Ropivacaine combined with either Dexmedetomidine or Clonidine	Assessment of block quality by calculation of composite score of bromage scale and duration of analgesia was recorded by patient response.
3. Total dose of rescue medication consumption (tramadol and Diclofenac)	Assessment of block quality by calculation of composite score of bromage scale and duration of analgesia was recorded by patient response.
in 24 hrs.	Assessment of block quality by calculation of composite score of bromage scale and duration of analgesia was recorded by patient response.
as adjuvants injected perineurally.	Assessment of block quality by calculation of composite score of bromage scale and duration of analgesia was recorded by patient response.
2. Number of Rescue analgesic given in 24 hours in both groups	Assessment of block quality by calculation of composite score of bromage scale and duration of analgesia was recorded by patient response.

Secondary Outcome Measures

Name	Time	Method
1. NRS pain scores at rest (NRS-R) & at movement (passive/active) NRS-M	of operated upper limb in first 24 hours.

Trial Locations

Locations (1): Dr S.N. Medical College and associate group of hospital
🇮🇳
Jodhpur, RAJASTHAN, India
Dr S.N. Medical College and associate group of hospital
🇮🇳Jodhpur, RAJASTHAN, India
Dr Anjali Singh
Principal investigator
8584998411
dranjalisingh57@gmail.com