行為激活對輕微抑鬱的療效研究
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 230
- 试验地点
- 1
- 主要终点
- Reduction of self-reported depressive symptoms
研究概览
简要总结
行為激活對輕微抑鬱的療效
研究设计
- 研究类型
- 干预性研究
- 主要目的
- 随机平行对照
- 盲法
- Single
入排标准
- 年龄范围
- 18 至 —（—）
- 性别
- All
入选标准
- •Aged 18 years or above;
- •Score 5-9 by Patient Health Questionnaire depression scale (PHQ-9).
排除标准
- •major depression within the past 6 months;
- •lifetime history of other psychiatric disorders including generalized anxiety disorder, psychosis, schizophrenia and bipolar affective disorder, alcohol or substance abuse, presence of serious suicidal risk and medical illness with a prognosis of less than 6 months to live;
- •patients who are receiving current treatment (taking antidepressants or other psychotropic medications or enrolled in any form of psychological interventions) for any depressive disorders or symptoms.
研究组 & 干预措施
Behavioral Activation
Behavioural activation: The Martell and Colleagues 2010 protocol will be used for the content of group BA intervention due to its established efficacy. The objective of the BA intervention is to identify, promote and reinforce activities and circumstances that are consistent with each participant’s long term goals.
Behavioral Activation (to be continued)
Specific content of the group BA will include psychoeducation with respect to well-being, setting both short and long term goals, the self-monitoring of activity and mood using activity logs to recognize the association between specific activities and mood,
Care As Usual
Participants assigned to the CAU will receive their medical care from the doctors who work in the general outpatient clinics. They are not referred to mental health intervention but receive active monitoring or regular minimal counselling from the primary care doctors.
Care As Usual (to be continued)
All participants will be informed that their health care utilization, including their visits and use of medications will be recorded using the electronic patient record systems.
结局指标
主要结局
Reduction of self-reported depressive symptoms
时间窗: Assessments with the outcome measures will take place at baseline, two, five months (3 months after intervention) and 1 year.
次要结局
- Incidence of DSM-IV major depression(1 year)
- Improvement in quality of life(measured at baseline, two, five months (3 months after intervention) and 1 year.)
- Utilization of health services including visits to primary care doctors(measured at baseline, two, five months (3 months after intervention) and 1 year.)
- activity change and circumstantial change(measured at baseline, two, five months (3 months after intervention) and 1 year.)
- patients to rate their impairment in 3 life domains including work, social and family/home management(measured at baseline, two, five months (3 months after intervention) and 1 year.)
- Anxiety symptoms(measured at baseline, two, five months (3 months after intervention) and 1 year)
- Satisfaction with delivered care(measured at baseline, two, five months (3 months after intervention) and 1 year)
- Quality-adjusted life years(measured at baseline, two, five months (3 months after intervention) and 1 year)