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A clinical trial to study the effects of two fluids, normal saline and albumin in patients with severe dengue fever

Not Applicable
Conditions
Health Condition 1: null- with severe dengue fever
Registration Number
CTRI/2018/03/012781
Lead Sponsor
Dr Suchitra Ranjit
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

patients with severe dengue in critical phase

Exclusion Criteria

Infants and children admitted to the HDU/PICU with Severe Dengue with

a.Significant bleeding or drop in Hct requiring transfusion

b.Need for positive pressure ventilation ( NIV or invasive ventilation) at presentation to PICU

c.Co-infections: Bacterial sepsis, scrub

d.Patients who were fluid resuscitated prior to arrival

e.Admission in recovery phase of dengue

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1.Need for rescue colloids <br/ ><br>2.Need for ventilation (NIV/invasive ventilation) <br/ ><br>3.Organ failure <br/ ><br>4.Mortality <br/ ><br>Timepoint: on day 1 , 2 and 3 of admission and starting the fluid therapy <br/ ><br>
Secondary Outcome Measures
NameTimeMethod
1.Need for diuretic/hemo-dialysis/CRRT <br/ ><br>2.Duration of positive pressure <br/ ><br>3.Duration of PICU, Hospital stay <br/ ><br>Timepoint: during the period of hospitalization
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