Evaluation of the association between heart type fatty-acid binding proteins and high sensitive troponin and postoperative myocardial infarction in patients undergoing cardiac-surgery
Withdrawn
- Conditions
- heart attackmyocardial infarction10028593
- Registration Number
- NL-OMON41530
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- Not specified
- Target Recruitment
- 800
Inclusion Criteria
Patients over 18 years, undergoing isolated coronary artery bypass grafting (CABG), isolated valve surgery (aortic valve replacement, mitral valve repair or replacement) or combined CABG and valve surgery in the University Medical Center Utrecht
Exclusion Criteria
Emergency surgery, (suspected) sepsis or pulmonary embolism, renal failure (defined as Glomerular Filtration Rate < 40 ml/min).
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Measurements: From all patients* blood samples will be obtained before, during<br /><br>and after surgery to measure H-FABP en troponin levels. Other relevant<br /><br>information will be obtained from the Electronic Patient Record system and from<br /><br>the Anesthesia Information and Management System (AIMS).<br /><br>The primary end-point is myocardial infarction. The occurence of postoperative<br /><br>myocardial infarction is imported from the Board Heart interventions<br /><br>Netherlands registry (BHN registry). This particular item is standardly filled<br /><br>out for all cardiac surgery patients in this hospital by the department of<br /><br>cardiology independent of this research.</p><br>
- Secondary Outcome Measures
Name Time Method <p>The secondary endpoint is mortality and hospital length of stay.</p><br>